Hypogonadism is a medical condition in there is a reduction in the levels of testosterone reduction. Testosterone has a significant function in regulating male sexual health. It also has a vital role in semen production and growing male sexual characteristics. Hypogonadism is associated with testosterone deficiency and leads to symptoms like reduced libido and infertility. These signs may also impact a person’s confidence and his general health.
Hypogonadism happens whenever the sex hormones are produced very little or no hormones. The sexual hormones, also known as gonads, are mainly the testes in males and the ovaries in girls. Sex hormones help regulate secondary sexual characteristics, including breast growth in girls, growth in guys, and pubic hair development. Sex hormones play a role in the menstrual cycle and sperm production.
Types of Hypogonadism
#1. Primary Hypogonadism
Primary hypogonadism is the condition in which there are abnormal or insufficient sex hormones this can happen due to any abnormality in the sex hormones. Scientifically the sex hormones receive signals from the brain to produce hormones but due to the defects in the hormones, this task cannot be accomplished.
#2. Secondary Hypogonadism
Secondary hypogonadism is the condition in which there are abnormalities in the brain which may lead to or insufficient sex hormones and secondary hypogonadism. This can happen due to any defect in the sex hormones. Scientifically there is a problem in the hypothalamus and pituitary of the brain that is why hormones have no control over its functions due to the abnormalities in the hormones.
The connections between hypogonadism and metabolic ailments are interdependent. Individuals with metabolic abnormalities like the ones who characterize diabetes and metabolic syndrome have a higher risk of testosterone deficiency. People that are hypogonadal will also be at a higher risk of metabolic disorders.
#4. Causes of primary hypogonadism
There can be different possible causes of primary hypogonadism, but the following conditions may contribute the most to develop primary hypogonadism.
- Autoimmune diseases
- Chronic infections
- Kidney diseases
- Liver diseases
- Exposure to radiation
- Genetic disorders
#5. Causes of secondary hypogonadism
The following are the essential causes of secondary hypogonadism
- Genetic defects
- Nutritional deficiencies
- Exposure to radiation
- Bleeding in pituitary
- Chronic infections
Testosterone deficiency or Hypogonadism is a curable condition, and many men experience greater testosterone level because of therapy. But several testosterone deficient men do not know they are testosterone deficient, and so do not seek out treatment for hypogonadism. In such conditions, hypogonadism increases the risk of a variety of other ailments or illnesses.
No increase in mortality has been seen in patients with hypogonadism. Morbidity for people involves infertility and an increased risk of osteoporosis. In women, a heightened probability of acute osteoporosis is reported. In men, hypogonadism causes diminished muscle power and sexual malfunction. Men and women with hypogonadism may lead to a healthy lifestyle using hormone replacement.
#2. Therapies to treat hypogonadism
Testosterone replacement therapy has shown benefits concerning sexual performance and total health for men with hypogonadism which is not age or illness-related.
Testosterone replacement therapy is only going to be prescribed by a physician after a blood test and clinical evaluation diagnosed with testosterone deficiency. The objective of testosterone replacement treatment is to raise blood glucose to normal levels. Increasing testosterone levels generally lead to apparent advantages.
#3. Hormone Replacement Therapy
Typically, hypogonadism may be treated effectively with HRT. This therapy includes taking drugs containing the hormone your body is missing, like testosterone, progesterone, and estrogen, or adrenal hormones to replace those the human body no longer produces. The most comfortable and most effective treatment for men and females using hypogonadotropic hypogonadism is a replacement for sexual steroids. When fertility is needed, an alternative treatment for men with hypogonadotropic hypogonadism is the management of pulsatile LHRH or shots of hCG and FSH.
#4. Gonadotrophin therapy
Gonadotrophic medications are effective in enhancing fertility for both men with secondary hypogonadism. Treatment with two hormones, human chorionic gonadotrophin, and human menopausal gonadotrophin, improves sperm production and maturation in over 90% of guys who acquired hypogonadism subsequent puberty. Remedy employing a mix of FSH and hMG raises the concentration of sperm from the semen at some 80 percent of guys. But it ought to be mentioned that the studies that produced these outcomes involved just a few of men, and additional studies are required to determine the efficacy of gonadotrophin treatment in enhancing fertility because of hypogonadal men.
#5. Injectable testosterone
Injectable testosterone has become the most typical kind of testosterone replacement treatment.
The health care provider will prescribe the right dose of testosterone, dependent on the intensity of the illness and based upon the results to the treatment. Irrespective of the testosterone dosage prescribed, testosterone could be treated in several ways.